It is well known that biological functions of cells can be controlled by applying external stimuli such as chemical reagents, changing temperature, and so on. Thus far, non-thermal atmospheric pressure plasma has been used to control activities of cells. The plasma-generated active species can be used to affect cells. Here, we used plasma stimulation for controlling differentiation of cells.

We are investigating plasma stimulation effects on differentiation of murine myoblast cells, C2C12 and neuroblast cells PC12.

With the collaboration of life scientist, we have published a paper of plasma exposure of human induced pluripotent stem cells.

“Non-thermal atmospheric-pressure plasma potentiates mesodermal differentiation of human induced pluripotent stem cells”

Kobayashi el al., Heliyon,

https://doi.org/10.1016/j.heliyon.2022.e12009